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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6537ea07f23fd17c46880221a1fce39919bf2203585dffd6b8a078b6248b68a6' 
  AND token = 'KS6k8Z1s7TKSVeY5KkQmrCLeMk/+U7j9f6k+vMM9UhI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}