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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a72ce9c28d61d70230447a60118a7351febae011483eedc76ad5a5cb98f1d18b' 
  AND token = 'iCSuajDb9/c5IMVbk0bFRx+V88T8KY9A+BYJ5VkXy0o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}