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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '60e2ad335c869d02b9126161d1d779280fcc1aa57a8f2fa85a44dd2e42283ffc' 
  AND token = 'XDBUZNaHdM8eVmUZEIioneHuFhvZT7O2qnuSqEKdkNs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}