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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a8ed214f14f9f9a3a8cb2168391c621575a015cb454e083fa22f23118b4a25c' 
  AND token = 'EnOsZ9sExIyvVS8TM8sjkfcYoKMKuDbe55SvBv0OgKE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}