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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a54caaf8263c492dacf269ba0763e0bd143df8ace2ebf83156248a3679954692' 
  AND token = 'Wl26D8o9Gdid8UpZ1wmMrCZxS+ugUfO8HblZWNRFIZ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}