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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7749e074926cebcac027a5b3a8ed25a1e004f9130adecf1b1df79b62e76b2be2' 
  AND token = 'kCusfT8SVKjGXCDWQ7ChkPPBH3iMrFa+q6FtRy2MLWs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}