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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5770081a0fcee8f72ec98b0a1b5981f9e2aab2206afdb7069c03cbf3496ab18c' 
  AND token = 'TxGDHLO9unT//mr/kiyH4gOxXghq4VZbRx/zknIlKFg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}