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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9929b297c58b4a571b6656eccdf1c0c41b968aff22c5feeed3a5af4452cc96c' 
  AND token = 'In2VJYCe2DMieD9FbJJzvozoF3QkmDPT5UXK/Y5tiAM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}