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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e1026b26363c28f34c7291e9acb9aa3f90c941d5d993704c363acadea366f03' 
  AND token = 'PtOdXNissF5YUI+K4VEuH57xRhL+b6ypvLG/6MpmXR0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}