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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4616762f765a6bbc65c36d0b26e5c67f6abd756f7926bd921dcf09320f9396fe' 
  AND token = 'YVPnJ2jIIY7HWiVD0GYoLLn0/XnT6dp5ecIKJy5DpsM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}