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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ecac04f22f93f9fc4989c2b37b70017610dc1a18859c15f084f456561bd3a6f' 
  AND token = 'xB7ecMc6ATt8MsXPR2k7z4s6soR2lsZtJPjVWsd46DM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}