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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7fc4eaa8a47066390393b42ee3ec22dc32feda1747e5ce625ec6d5c24d376782' 
  AND token = 'yX4CCkOUNWx5+pCyfVPTnOwcfWjCjHubyR3UK29TTY0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}