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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4370c64838542cf5e1888de947b50e66740b17c637216d3e7c116b678d9bfa4f' 
  AND token = 'gMBPvwq/OyQBzOIgNm7N703tqWwsvlbagxtg0nCHq28=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}