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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8b1400e498655e457dbe9c4fcdae5cc4d2f9a410e598953898954b3a0772dab' 
  AND token = '2BeR8mcRJ8ykZedCTcL2uU5+4wxvsiRZEpcXX0TpLX0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}