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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '71605c9b984e5be2bcbd0334edc2d05c65cce879b36ef297b4e2c694da487e8f' 
  AND token = 'fS0Cva4nJtY/OGDa+MrBJC6FB6xPr6fbFukG1eUg0lE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}