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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57a531b15dba5fddc3d66206a3417754371c1915f9888b2a89f456741d59a986' 
  AND token = 'MUWZbJXdbsH63NwsoJ5McLBhiAedGkCDZP/ypb1jfxA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}