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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dfc67d39e175f610fc0e505c6001732179b08162b64b2806dcc956e35f292aea' 
  AND token = 'vk1R1OIlNw1eO/8+ChjFiNjhUSwfpwFLMF1XFqsSVFc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}