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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7bf358cc23930ad92755ef6ef516d955bef860b265ce901e56c6eeab8ff2a4d' 
  AND token = 'Tz15b8a8+AMb30SVWMQkkMNFiAeJe3o+lB0b3s5qH48=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}