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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2ca89118bbe8c16892fb921527eacccf6be0fe90fd3fcf7386dd42fbf2683c0' 
  AND token = 'b7oyIL5hnCOU+pgDbRLvKFvH3iYHtguZeEYZC+0tslM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}