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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1629139a08862f42cdf2b5e67e153f8aca3cd92d08fb6c5ed78c12194269bbe' 
  AND token = 'ewQc7exvXrgJLTejMXYQqOD7RY+sOSSAxkZ7Rsxx9Uo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}