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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '654077dcc5e54f32a248acc17b9fa77ad6b1765df6760f9fd5f62a002c79750e' 
  AND token = 'c+R8smInyri8F9rX8KWM7VS6SfZImREhUF93NZFO3uQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}