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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a64d3adfdd6c6a5a3ab4f2487451607b827eb74aec899a9165c4e47c4cc40de' 
  AND token = 'xatvI1XHjXE3g4sy95XtxjCsPu1Ml6y1I+2AVjIXwcY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}