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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd9956e28293a213558d4b95a712bb60044eda8b100b093fa8919ec2d9da2eb1' 
  AND token = 'VF5uAiUmovBDeX+t9JszMGo2a7iUI82f25EWha456es=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}