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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9eb7120df4e1c9cfcd8ba810e4154e8ae72abcac5fc82bbfb6000c5d48c85827' 
  AND token = 'ILUtQhcs1dicHZPWfb1TkqrJCY79psEYbjahtj4v3Ik=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}