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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0645b2442e94b5f511fb480ef25115712f748a0700c78e9b421c5a7e6d68a90a' 
  AND token = '891+6INKe6rl6/hXvyZ9/fusbpJrWV0sE2ZlTvWkTmQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}