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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0f35186b9dfe22f9e7fcedc8c511f43752ae6232d7236d338db262f861fb15d' 
  AND token = '5yJPMwywOMsz4IEhqp556eEShDQ4sCkpYjz9LG+xiso=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}