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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fdfc1d7adb9e229dbac783fde14db9cab0e1bb8de2de4192665c9f1d672d70a1' 
  AND token = 'EdSKB6zAZ4e8p+TJODK3JYmnC1gPXs4bMYY+e8mOWyw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}