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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6245f89e8e787efba01929a521571ea7409767c438186ea4151723940d857b9d' 
  AND token = 'iSGH8I4xjj4flxrBcU26TR0pXnjtagKw3ThJei5+iMk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}