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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a09ab5009f32082a6cade6f2848d11891974caea8f6306483e065114f77af670' 
  AND token = 'cxsY+qe7OZMFN8JtzH58WHefgMYux4xYi9NqVDx4RdI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}