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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25b416a34393f721d22254411a6d08980fca87df9febf92c3999f5928992a026' 
  AND token = '5Xd0bzlV3R5BMJXfvNwiT1tyOhx9ZvfsyWSF0oG6AyE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}