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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd66a2e23e5c163a1f09e68bd10dae2da47667abd7daf97f53e62d4ddce20f9ae' 
  AND token = 'c0+PEUHdDSn07P6oOruvCwdQQ+/1COZHuENdlTdv3ZA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}