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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd38e5bdf8d131b895f24cd921909f0a23f88d0bc9b5a2dc8864cf0cc8b59a849' 
  AND token = '8wHcITj66pAAehM51VQihhwzcWJFco0JZ9Q7eSbCVMM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}