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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ffb8a74448852fd9a407afe3b59e1df5d40e9249409c61875a6dd436d39bb440' 
  AND token = '5nl24/XcoSz2cxwVTNXS9fvdSIM6iB447y5SxNGkTTM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}