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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fdff9a6b1b5f2a40b9f72332f42c242beb81d25e2f356e8b9820ef0d1edddfdd' 
  AND token = 'G2hiZ5tYlF40SskLuZISj4zFn67sUVb1180f46ttmLU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}