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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aed7fd1420e87abd95fc89bea29615b012b735e52f7add711a3f1e0222cef43d' 
  AND token = 'NxUc+bbD0diIsb4bXpXBeZDRKhGpHhXdE4NAb9Cy1tY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}