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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ea6fb234e3b90139e917e187343f5d75b9ee222077ac323b6ee6bd1fb5286b1' 
  AND token = 'blyGDAVIUrYvGQstGNtP5nq6IAiqGFcAEcZVft8k6wg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}