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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8e85346d316e7c57ac376208b8802ada4cdbbb6819515134dbb8566d34a7324' 
  AND token = '5DES9QHNYJ9OsmMVx0ciMHvtNho83NjmWLehM9HwJ3o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}