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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f0e1cf7bde5ff126bf119d17932cfffd29b04634e9fd55f9a80c9c1e2ec5628' 
  AND token = 'sfuRiJ52GM7zNPSJHqinSKrU03c3O/ZIQdFVJoNVuh0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}