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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '224e8ad2d266921ef11effcc3506e8c9672b1180ef46a26d7b569be1126bddde' 
  AND token = '4oSDEctSrio+upxGPW926KBBs30ScY/293oFCTwtd/s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}