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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49ca4205c5f5cad54a6f62898a7855e83c37b2a713bfc04a69651585a50804ac' 
  AND token = 'Bmu+vnrNw8QfREa4vrgpV3AwI5oEG8zLLPFvlvdLlCw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}