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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2800f1998d39b55843bfaf60e8db1cdc2424b5f96abafd3e0cbac1a67786f774' 
  AND token = '4GCqkXfUHObkE67qrEbngYFBspzQpe6GHlzi54nNHkI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}