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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48f8832baf783e45958445b261be8644f9f3b271e43f64e9ced816b699f9fb46' 
  AND token = 'eYJNFubeBdCTeVy5gfI/ku//VYoC1ixPOyW82Akt+sk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}