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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9046b3e4c478b064c3645b8c4f209adfc7628ecd3c70dde6ed5b286877c0a2c2' 
  AND token = 'DVHF58qOb+mO79qZLz0MIbdBYONhgR9yEbQA4ATH+a0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}