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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b3ac11c3d6da51acbd353507a25a21331087017eb801247ed61b3b75fc6a4d2' 
  AND token = 'kf9NxHG9XFPnIARjAZnEt89PM6N4XcXTxLL1mgjOSz4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}