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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1900ef0b87f5ea9e21415108486a153365aee59c2dee8ad2242023708be8aec7' 
  AND token = 'kwhbm/pG+X5xmeBOH08WiKbXa/sMx2QkMZfVmdic1k4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}