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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb6c0995b7b955ea85fa15417d0cc75c0824f153bb1348e0ee43f9e65399e7c0' 
  AND token = 'XWRf2P1adZc5pu7SkxbbqkegHwvtBbBP5YF6Usz/mqc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}