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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '049dce836be5adcf7f1716a9c7c16e843a480016574f841977861936738fed4e' 
  AND token = 'YzBMqJzA/ZqTaM851bIpuWTVqb7nU7nhzScNn76yKMk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}