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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bd38ddb4ed204ce1d0c75c29f81ee13d77e53afc7daf871af859e36b275605cf' 
  AND token = 'UFOTS09o/NtwC5sCB+rfsQSmXmAUXnx7ufBBrOMd6xI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}