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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '60b1d935d48fe9537d2b29336ef892b537fc7db346f0c15580644d16828acf8a' 
  AND token = 'FQ6cBpQ6lO6PatuYkilAdxOqSW1FOdfsMqiQf0bwXOo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}