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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4c7765030ac8b13bced85307369563fca3fdf0fbe282bcd04a30bf9a6e74ee1' 
  AND token = 'A7y8UMipXzyAMey1PRz9Ff1nltmt6IumaLr/8wnAGxM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}